中国医学科学院学报

高级检索
中国医学科学院学报

中国医学科学院学报 ›› 2019, Vol. 41 ›› Issue (3): 402-407.doi: 10.3881/j.issn.1000-503X.10579

• 综述 • 上一篇    下一篇

眼肌型重症肌无力的研究进展

吴雅俊,晏立,胡裕翔,饶杰,许晓璇,程艺,吴娜,吴晓蓉()   

  1. 南昌大学第一附属医院眼科,南昌 330006
  • 收稿日期:2018-05-28 出版日期:2019-06-30 发布日期:2019-07-04
  • 通讯作者: 吴晓蓉 E-mail:wxr98021@126.com
  • 基金资助:
    国家自然科学基金地区项目(81760179);国家自然科学基金地区项目(81360151);江西省自然科学基金面上项目(20171BAB205046);江西省教育厅重点项目(GJJ160033);江西省卫生厅一般项目(20185118);江西省卫生计生委中医药科研课题(2017A001);江西省基层卫生适宜技术星火推广计划项目(20188007);江西省卫生计生普通计划(20141031);江西省教育厅一般项目(GJJ13147);江西省科技支撑计划项目(20141BBG70027)

Research Advances in Ocular Myasthenia Gravis

WU Yajun,YAN Li,HU Yuxiang,RAO Jie,XU Xiaoxuan,CHENG Yi,WU Na,WU Xiaorong()   

  1. Department of Ophthalmology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China
  • Received:2018-05-28 Online:2019-06-30 Published:2019-07-04
  • Contact: Xiaorong WU E-mail:wxr98021@126.com
  • Supported by:
    Supported by the National Natural Sciences Foundation of China(81760179);Supported by the National Natural Sciences Foundation of China(81360151);The Natural Science Foundation of Jiangxi Province(20171BAB205046);The Key Foundation of Education Department of Jiangxi Province(GJJ160033);The Health Development Planning Commission Science Foundation of Jiangxi Province(20185118);The Chinese Medicine Research Project of Jiangxi Health and Family Planning Commission(2017A001);The Jiangxi Province Grass-roots Health Appropriate Technology Spark Promotion Project(20188007);The Jiangxi Provincial Health and FP General Plan(20141031);The General Project of Jiangxi Provincial Education Department(GJJ13147);The Foundation of Science and Technology Supported by Jiangxi Provincial(20141BBG70027)

摘要:

眼肌型重症肌无力(OMG)为神经-肌肉接头传递障碍所致的自身免疫性疾病,主要表现为波动性上睑下垂、复视,肌无力症状局限于眼外肌,其发病机制尚未完全阐明,某些抗体、补体、细胞因子等可能参与疾病的发生。OMG的诊断、治疗较为明确,近年来新的诊断、治疗方式相继报道,本文总结了OMG的发病机制、诊断和治疗进展,以期为临床诊断及治疗提供依据。

关键词: 眼肌型重症肌无力, 机制, 诊断, 治疗

Abstract:

Ocular myasthenia gravis(OMG)is an autoimmune disease caused by neuromuscular junction transmission disorders and manifested mainly as fluctuating blepharoptosis and diplopia,with the extraocular muscles as the main involveed sites.While the pathogenesis of OMG remains unclear,some antibodies,complements,and cytokines may be the contributing factors.The diagnosis and treatment of OMG have been defined in recent years.This article reviews the pathogenesis,diagnosis,and treatment of OMG.

Key words: ocular myasthenia gravis, pathogenesis, diagnose, treatment

中图分类号: