中国医学科学院学报

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中国医学科学院学报

中国医学科学院学报 ›› 2020, Vol. 42 ›› Issue (6): 771-775.doi: 10.3881/j.issn.1000-503X.12731

• 论著 • 上一篇    下一篇

超声引导下射频消融治疗T1bN0M0期甲状腺乳头状癌的短期疗效分析

肖静1,2,兰雨1,2,阎琳2,张明博2,张艳2,谢芳2,宋青2,罗渝昆1,2(),唐杰1,2   

  1. 1南开大学医学院,天津 300071
    2中国人民解放军总医院第一医学中心超声诊断科,北京 100853
  • 收稿日期:2020-03-17 出版日期:2020-12-30 发布日期:2021-01-11
  • 通讯作者: 罗渝昆 E-mail:lyk301@163.com
  • 基金资助:
    国家自然科学基金(81771834)

Short-term Outcome of T1bN0M0 Papillary Thyroid Cancer after Ultrasonography-guided Radiofrequency Ablation

XIAO Jing1,2,LAN Yu1,2,YAN Lin2,ZHANG Mingbo2,ZHANG Yan2,XIE Fang2,SONG Qing2,LUO Yukun1,2(),TANG Jie1,2   

  1. 1School of Medicine,Nankai University,Tianjin 300071,China
    2Department of Ultrasound,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China
  • Received:2020-03-17 Online:2020-12-30 Published:2021-01-11
  • Contact: LUO Yukun E-mail:lyk301@163.com
  • Supported by:
    National Natural Sciences Foundation of China(81771834)

摘要:

目的 探讨超声引导下射频消融(RFA)治疗T1bN0M0期甲状腺乳头状癌的短期疗效。方法 回顾性分析2014年4月至2019年1月经超声引导下RFA治疗的89例T1bN0M0甲状腺乳头状癌患者。超声引导下RFA采用经峡部入路和移动消融法。消融前及消融后即刻、1、3、6、12个月及其后每6个月进行常规超声和超声造影检查。结果 89枚甲状腺乳头状癌均成功消融,术中未见严重并发症。平均随访时间为(18.8±7.3)个月。随访过程中消融灶体积不断缩小,38个(42.7%)消融灶消失,消融后30个月时的体积缩小率为(99.2±2.3)%。随访过程中2例(2.2%)患者出现复发,1例(1.1%)患者出现颈部淋巴结转移。结论 超声引导下RFA可安全、有效地治疗T1bN0M0期甲状腺乳头状癌患者。

关键词: 超声, 射频消融, 甲状腺乳头状癌

Abstract:

Objective To investigate the short-term outcome of T1bN0M0 papillary thyroid cancer after ultrasonography-guided radiofrequency ablation(RFA). Methods Eighty-nine patients with T1bN0M0 papillary thyroid cancer who were treated with ultrasonography-guided RFA in our center from April 2014 to January 2019 were retrospectively analyzed.Trans-isthmus approach and moving shot technique were used during the RFA procedure.Ultrasonography and contrast-enhanced ultrasonography were performed before ablation,and immediately,1,3,6 and 12 months after ablation and then every 6 months thereafter. Results RFA was performed in 89 cases of papillary thyroid cancer,and no major complications were observed during the RFA.The mean follow-up was(18.8±7.3)months.The ablation zones decreased gradually during follow-up,and 38 ablation zones(42.7%)completely disappeared.The volume reduction rate was(99.2±2.3)% 30 months after ablation.During follow-up,2 patients(2.2%)developed tumor recurrence and 1 patient(1.1%)developed cervical lymph node metastasis. Conclusion Ultrasonography-guided RFA may be a safe and effective method for patients with T1bN0M0 papillary thyroid cancer.

Key words: ultrasonography, radiofrequency ablation, papillary thyroid cancer

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