中国医学科学院学报

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中国医学科学院学报

中国医学科学院学报 ›› 2012, Vol. 34 ›› Issue (5): 488-491.doi: 10.3881/j.issn.1000-503X.2012.05.009

• 论著 • 上一篇    下一篇

磁共振弥散加权成像及增强扫描在早期子宫内膜癌分期中的应用

安奇,杨靖,朱越   

  1. 沈阳市第四人民医院放射科,沈阳 110031
  • 收稿日期:2012-05-15 修回日期:2012-11-07 出版日期:2012-10-31 发布日期:2012-10-31
  • 通讯作者: 杨 靖 电话:13998808481,电子邮件:goodbabyyj@126.com E-mail:goodbabyyj@126.com

Diffusion Weighted Imaging and Contrast-enhanced Magnetic Resonance Imaging in the Evaluation of Early Stage Endometrial Cancer

AN Qi,YANG Jing,ZHU Yue   

  1. Department of Radiology, Fourth Peoples Hospital of Shenyang City,Shenyang 110031, China
  • Received:2012-05-15 Revised:2012-11-07 Online:2012-10-31 Published:2012-10-31

摘要: 目的 应用磁共振成像(MRI)相关扫描序列对早期子宫内膜癌患者进行分期诊断的评价。方法 回顾性分析27例术后病理诊断分期为Ⅰ~Ⅱ期子宫内膜癌患者的磁共振盆腔常规平扫、弥散加权成像(DWI)结合表观扩散系数-T2加权像(ADC-T2WI)融合图像、T1加权像(T1WI)增强扫描序列,分析几组扫描序列对早期子宫内膜癌分期诊断的准确率。结果 MRI盆腔常规平扫、DWI结合ADC-T2WI融合图像、T1WI增强扫描对早期子宫内膜癌分期诊断的准确率分别为66.7%、85.2%和92.5%,DWI结合ADC-T2WI融合图像诊断病变侵犯肌层深度大于1/2的敏感度、特异度及诊断准确率分别为82.3%、75%和85.2%。结论 MRI盆腔常规平扫序列对早期子宫内膜癌分期诊断存在一定的误差,在几组检查序列中诊断的准确率最低;DWI结合ADC-T2WI融合图像诊断的准确率比常规平扫序列明显提高;T1WI序列增强扫描对病变范围显示最为清晰,对病变肌层浸润程度的判定最为准确,评估早期子宫内膜癌的分期准确率最高。

关键词: 子宫内膜癌, 磁共振成像, 弥散加权成像, 表观扩散系数

Abstract: Objective To assess the values of diffusion weighted imaging and contrast-enhanced magnetic resonance imaging (MRI) in the evaluation of early endometrial cancer. Methods We retrospectively analyzed the imaging data of 27 patients with pathologically confirmed stage Ⅰ-Ⅱ endometrial cancer. These patients received pelvic magnetic resonance imaging, diffusion weighted imaging with apparent diffusion coefficient-T2 weighted imaging fusion images(ADC-T2WI), and T1 weighted imaging (T1WI) of contrast-enhanced scan sequence. The accuracies of these image modes were analyzed and compared. Results The accuracy of routine pelvic MRI scan, diffusion weighted imaging with ADC-T2WI fusion images, and T1WI of contrast-enhanced scan for the early diagnosis of endometrial cancer was 66.7%, 85.2%, and 92.5%, respectively. The sensitivity, specificity and diagnostic accuracy of diffusion weighted imaging with ADC-T2WI fusion images in the diagnosis of lesions with a 1/2 depth of muscle were 82.3%, 75%, and 85.2%. Conclusions Routine pelvic MRI scan sequence has certain errors for the early diagnosis of endometrial cancer. On the contrary, the diffusion weighted imaging with ADC-T2WI image fusion has remarkably increased diagnostic accuracy. The T1WI of contrast-enhanced scan can clearly display most of the lesions by identifying the muscular infiltrations, and therefore can provide the most accurate information for the staging of early endometrial cancer.

Key words: endometrial carcinoma, magnetic resonance imaging, diffusion weighted imaging, apparent diffusion coefficient

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