中国医学科学院学报

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中国医学科学院学报

中国医学科学院学报 ›› 2016, Vol. 38 ›› Issue (2): 210-216.doi: 10.3881/j.issn.1000-503X.2016.02.015

• 论著 • 上一篇    下一篇

城乡青少年脂代谢状态及与低出生体质量等相关因素的关联分析

刘绍英1, 王彤2, 谢娟2, 职心乐2()   

  1. 1天津市静海县疾病预防控制中心,天津 301600
    2天津医科大学 公共卫生学院流行病与卫生统计学系,天津 300070
  • 收稿日期:2015-04-13 出版日期:2016-02-15 发布日期:2016-04-10
  • 作者简介:

    通信作者:职心乐 电话:022-83336618,电子邮件:zhixinyue@tmu.edu.cn

An Analysis on the Association between Lipid Metabolism and Low Birth Body Mass and Relative Factors among Rural and Urban Adolescents

Shao-ying LIU1, Tong WANG2, Juan XIE2, Xin-yue ZHI2()   

  1. 1Tianjin Jinghai Centers for Disease Control and Prevention,Tianjin 301600,China
    2Department of Epidemiology and Biostatistics,School of Public Health,Tianjin Medical University,Tianjin 300070,China
  • Received:2015-04-13 Online:2016-02-15 Published:2016-04-10

摘要:

目的 探讨不同经济文化背景青春期少年的脂代谢状态以及脂代谢异常与低出生体质量等生命早期营养因素之间的相互关联。方法 2013年通过随机整群抽样方法选取城乡青春期少年共1 700例,对研究对象进行血脂测定以及问卷调查,获知相关危险因素信息。结果 正常出生体质量少年中,城市和乡村的女孩高密度脂蛋白水平高于男孩,低密度脂蛋白城市女孩高于男孩,乡村男孩和城市女孩的总胆固醇水平较高。低出生体质量少年中,城市男孩的总胆固醇水平较高,其他指标差异均无统计学意义。城乡之间比较发现,正常出生体质量少年中,高密度脂蛋白城市少年水平低于乡村,总胆固醇水平城市少年高于乡村少年,其他指标差异无统计学意义。不同出生体质量组比较显示,正常出生体质量组的高密度脂蛋白水平、低密度脂蛋白水平、三酰甘油和总胆固醇水平均高于低出生体质量组。可能影响青春期少年血脂状况的因素包括出生体质量、母亲孕期体质量异常增加、脂代谢异常家族史以及不吃早餐和存在不健康零食的习惯;收缩压异常和脉压差增高也与青春期血脂异常存在关联。结论 低出生体质量与青春期的脂代谢存在关联,低出生体质量以及家族史、生活饮食方式因素与青春期发生脂代谢异常有关。

关键词: 青春期, 脂代谢, 低出生体质量, 生命早期营养

Abstract:

Objective To analyze the status of lipid metabolism and the relationship between low birth body mass and lipid metabolism disorders in adolescents with different economic and cultural backgrounds. Methods Totally 1 700 adolescents from urban and rural areas aged 12-18 years were selected in 2013. The lipid profiles were determined,and a questionnaire-based survey was conducted. Results Among normal birth body mass adolescents, girls obtained a high density lipoprotein in both urban and rural areas, low density lipoprotein cholesterol level was higher for city girls, rural boys and urban girls obtained higher total cholesterol level, the differences all reached statistical significance. While among the low birth body mass adolescents, higher level of total cholesterol for urban boys was detected, with statistically significance. When compared between rural and urban areas, high density lipoprotein cholesterol level for urban adolescents was lower in normal birth body mass adolescents, while total cholesterol level for urban adolescents was higher, both with statistically significance. While the comparison between different birth body mass adolescents suggested that the normal birth body mass adolescents obtained a higher high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglyceride and total cholesterol level. When analyze the influenced factors of disorder of lipid metabolism, the results suggest that low birth body mass, maternal pregnancy body mass increasing, lipid homeostasis family history, absence of breakfast, unhealthy snack habit, abnormal of systolic blood pressure and pulse pressure increasing were related to the occurrence of dyslipidemia. Conclusions Low birth body mass is related with lipid metabolism in early puberty. Low birth body mass,family history of abnormal lipid metabolism,and poor diet habits can increase the risk of abnormal lipid metabolism in puberty.

Key words: adolescence, lipid metabolism, low birth body mass, nutrition early in life

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