Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (4): 519-527.doi: 10.3881/j.issn.1000-503X.10114
• Original Articles • Previous Articles Next Articles
WU Peng1, ZHANG Yujiao1, QIN Fang2, LIU Lan1, CUI Shujun1()
Received:
2017-10-18
Online:
2018-08-30
Published:
2018-09-08
Supported by:
CLC Number:
WU Peng, ZHANG Yujiao, QIN Fang, LIU Lan, CUI Shujun. Diffusion Tensor Imaging in Early Diagnosis and Prognostic Prediction of Intervertebral Disc Change in Patients with Brucella Spondylitis[J].Acta Academiae Medicinae Sinica, 2018, 40(4): 519-527.
Fig 2
CT appearance of the patients with BS,the bone hyperplasia of the adjacent vertebral body was hard,and the cartilage endplate was severely damaged A.the lumbar 3/4 intervertebral space was significantly narrowed,and the adjacent vertebral upper and lower margin was damaged;B. the lumbar 2/3 intervertebral space is significantly narrowed,adjacent to the upper and lower margin of vertebral body bone destruction,hyperplasia and sclerosis"
Fig 4
The intervertebral disc is involved in patients with BS A. high signal and intervertebral space on T2WI;B. low signal on T1WI;C.the transverse position of T2WI shows high signal with irregular edge;D. pathological findings: a large number of inflammatory cells infiltrate,along with the destruction of chondrocyte structures(HE staining,×200);E. the T2WI signal of multiple cervical vertebrae is uneven;F. STIR image shows obvious high signal;G. pathological findings: a large number of neutrophils,along with the disappearance of chondrocyte structures(HE staining,×200)"
Table 1
Comparison of intervertebral disc FA and ADC values of BS patients in different observation periods($\bar{x}$±s)"
部位 Location | ADC值ADC value(×10-4 mm2/s) | FA值FA value | ||||||
---|---|---|---|---|---|---|---|---|
对照组 Control group | BS患者急性期 BS patients acute stage | BS患者亚急性期 BS patients subacute stage | BS患者慢性期 BS patients chronic stage | 对照组 Control group | BS患者急性期 BS patients acute stage | BS患者亚急性期 BS patients subacute stage | BS患者慢性期 BS patients chronic stage | |
颈2/3 Cervical 2/3 | 1.67±0.32 | 1.77±0.43 | 1.78±0.41 | 1.76±0.40 | 0.58±0.32 | 0.60±0.29 | 0.61±0.31 | 0.59±0.21 |
颈3/4 Cervical 3/4 | 1.77±0.44 | 1.87±0.40 | 1.88±0.39 | 1.88±0.41 | 0.72±0.21 | 0.54±0.19 | 0.55±0.20 | 0.64±0.22 |
颈4/5 Cervical 4/5 | 1.65±0.42 | 1.89±0.52 | 1.88±0.51 | 1.81±0.49 | 0.73±0.22 | 0.52±0.31 | 0.55±0.19 | 0.67±0.24 |
颈5/6 Cervical 5/6 | 1.72±0.35 | 1.94±0.45 | 1.88±0.38 | 1.85±0.32 | 0.69±0.33 | 0.53±0.21 | 0.54±0.23 | 0.67±0.29 |
颈6/7 Cervical 6/7 | 1.70±0.33 | 1.87±0.32 | 1.86±0.35 | 1.86±0.31 | 0.77±0.18 | 0.75±0.20 | 0.77±0.19 | 0.78±0.21 |
颈7/胸1 Cervical 7/thoracic 1 | 1.73±0.41 | 1.75±0.39 | 1.76±0.44 | 1.74±0.29 | 0.75±0.15 | 0.74±0.14 | 0.76±0.17 | 0.76±0.19 |
胸1/2 Thoracic 1/2 | 1.63±0.22 | 1.69±0.30 | 1.64±0.27 | 1.65±0.33 | 0.65±0.23 | 0.63±0.32 | 0.64±0.28 | 0.65±0.19 |
胸2/3 Thoracic 2/3 | 1.67±0.31 | 1.69±0.32 | 1.68±0.31 | 1.68±0.29 | 0.70±0.30 | 0.66±0.29 | 0.69±0.28 | 0.70±0.29 |
胸3/4 Thoracic 3/4 | 1.72±0.41 | 1.73±0.39 | 1.72±0.40 | 1.72±0.23 | 0.69±0.29 | 0.67±0.28 | 0.68±0.27 | 0.69±0.26 |
胸4/5 Thoracic 4/5 | 1.70±0.43 | 1.71±0.33 | 1.71±0.30 | 1.71±0.29 | 0.70±0.21 | 0.68±0.25 | 0.69±0.24 | 0.70±0.19 |
胸5/6 Thoracic 5/6 | 1.72±0.44 | 1.90±0.32 | 1.92±0.33 | 1.75±0.29 | 0.68±0.23 | 0.66±0.24 | 0.67±0.24 | 0.67±0.30 |
胸6/7 Thoracic 6/7 | 1.88±0.21 | 1.89±0.22 | 1.87±0.42 | 1.88±0.23 | 0.71±0.33 | 0.68±0.31 | 0.69±0.35 | 0.70±0.37 |
胸7/8 Thoracic 7/8 | 1.78±0.33 | 1.90±0.32 | 1.89±0.22 | 1.80±0.34 | 0.80±0.21 | 0.65±0.25 | 0.75±0.19 | 0.79±0.22 |
胸8/9 Thoracic 8/9 | 1.69±0.45 | 1.88±0.32 | 1.87±0.42 | 1.83±0.24 | 0.79±0.22 | 0.67±0.23 | 0.70±0.20 | 0.75±0.24 |
胸9/10 Thoracic 9/10 | 1.73±0.34 | 1.98±0.22 | 1.96±0.34 | 1.90±0.32 | 0.75±0.31 | 0.59±0.21 | 0.64±0.23 | 0.71±0.29 |
胸10/11 Thoracic 10/11 | 1.78±0.29 | 1.87±0.34 | 1.86±0.23 | 1.82±0.31 | 0.76±0.29 | 0.56±0.23 | 0.63±0.25 | 0.68±0.24 |
胸11/12 Thoracic 11/12 | 1.69±0.34 | 1.88±0.21 | 1.85±0.23 | 1.79±0.34 | 0.73±0.31 | 0.60±0.29 | 0.65±0.23 | 0.69±0.25 |
胸12/腰1 Thoracic 12/lumbar1 | 1.78±0.22 | 1.89±0.24 | 1.87±0.26 | 1.84±0.35 | 0.69±0.29 | 0.61±0.23 | 0.64±0.25 | 0.67±0.24 |
腰1/2 Lumbar 1/2 | 1.73±0.32 | 1.80±0.32 | 1.81±0.29 | 1.74±0.33 | 0.77±0.33 | 0.64±0.32 | 0.69±0.11 | 0.75±0.26 |
腰2/3 Lumbar 2/3 | 1.69±0.32 | 1.75±0.29 | 1.74±0.30 | 1.70±0.34 | 0.76±0.19 | 0.63±0.22 | 0.69±0.19 | 0.75±0.32 |
腰3/4 Lumbar 3/4 | 1.73±0.23 | 1.89±0.21 | 1.87±0.30 | 1.80±0.29 | 0.77±0.31 | 0.53±0.33 | 0.64±0.34 | 0.70±0.30 |
腰4/5 Lumbar 4/5 | 1.70±0.33 | 1.85±0.23 | 1.84±0.34 | 1.79±0.29 | 0.78±0.29 | 0.60±0.23 | 0.66±0.25 | 0.75±0.33 |
腰5/骶1 Lumbar 5/sacral 1 | 1.72±0.23 | 1.86±0.33 | 1.83±0.24 | 1.80±0.25 | 0.77±0.24 | 0.64±0.11 | 0.67±0.25 | 0.72±0.26 |
F | 3.527 | 175.500 | 160.640 | 174.200 | 5.762 | 83.330 | 79.550 | 69.560 |
P | 0.078 | 0.001 | 0.002 | 0.001 | 0.069 | 0.000 | 0.001 | 0.002 |
Table 2
Comparison of ADC and FA values of intervertebral disc before and after treatment at different stages($\bar{x}$±s)"
分期 Phase | ADC 值 ADC value | |||||
---|---|---|---|---|---|---|
治疗前 Before treatment | 治疗后6个月 6 months after treatment | 治疗后12个月 12 months after treatment | P1 | P2 | P3 | |
急性期Acute stage(n=15) | 1.83±0.33 | 1.71±0.14 | 1.68±0.13 | 0.007 | 0.021 | 0.006 |
亚急性期Subacute stage(n=8) | 1.81±0.23 | 1.66±0.18 | 1.65±0.19 | 0.005 | 0.007 | 0.013 |
慢性期Chronic stage(n=13) | 1.79±0.34 | 1.65±0.18 | 1.65±0.17 | 0.002 | 0.012 | 0.089 |
分期 Phase | FA值 FA value | |||||
治疗前 Before treatment | 治疗后6个月 6 months after treatment | 治疗后12个月 12 months after treatment | P1 | P2 | P3 | |
急性期Acute stage(n=15) | 0.62±0.21 | 0.73±0.19 | 0.75±0.22 | 0.023 | 0.008 | 0.025 |
亚急性期Subacute stage(n=8) | 0.64±0.18 | 0.74±0.18 | 0.76±0.21 | 0.019 | 0.002 | 0.034 |
慢性期Chronic stage(n=13) | 0.67±0.23 | 0.74±0.22 | 0.77±0.23 | 0.031 | 0.043 | 0.044 |
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