Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (6): 797-802.doi: 10.3881/j.issn.1000-503X.10374

• Original Articles • Previous Articles     Next Articles

Risk Factors of Asthma Attack in An Open Cohort

BAI Chenxiao1,WANG Liwen1,JIANG Di1,CHEN Ou1,2()   

  1. 1Department of Community Nursing,Nursing School of Shandong University,Jinan 250012,China
    2Cheeloo Research Center for Biomedical Big Data,Shandong University,Jinan 250012,China
  • Received:2018-03-07 Online:2018-12-20 Published:2019-01-03


Objective To investigate the risk factors of asthma attack.
Methods In this open cohort study,74 492 initially healthy subjects aged 20 years or more in a longitudinal multi-center health management cohort in Shandong province from January 2007 to December 2015 were enrolled in this study. These subjects had no baseline bronchial asthma or other chronic airway disease and did not migrate to other provinces in the past 10 years. All subjects were followed up till 2016,and the asthma attack and its influencing factors were analyzed. The baseline data including sociodemographic data,smoking history,disease histories,and family disease histories were collected and analyzed by Poisson regression analysis.
Results The regression analysis showed that age between 40 and 50 years(RR=3.3,95%CI=1.8-6.0),female(RR=1.6,95%CI=1.1-2.3),nasal polyps(RR=9.5,95%CI=2.3-39.6),pneumonia(RR=6.5,95%CI=3.7-11.2),bronchitis(RR=8.7,95%CI=5.1-14.7),and chronic obstructive pulmonary disease(RR=6.6,95%CI=3.1-13.8) significantly increased the risk of asthma attack.
Conclusion Age,gender,and previous histories of certain respiratory tract diseases increase the risk of asthma attack.

Key words: bronchial asthma, medical history, Poisson regression

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