Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2019, Vol. 41 ›› Issue (1): 53-56.doi: 10.3881/j.issn.1000-503X.10418

• Original Articles • Previous Articles     Next Articles

An Improved Method for Electroencephalographic Detection of Epileptic Discharge

SHI Xinze,XU Qi()   

  1. National Key Laboratory of Medical Molecular Biology,Institute of Basic Medical Sciences,CAMS and PUMC,Beijing 100005,China
  • Received:2018-03-27 Online:2019-02-28 Published:2019-03-06
  • Contact: Qi XU E-mail:xuqi@pumc.edu.cn
  • Supported by:
    Supported by the National Natural Sciences Foundation of China(81501131);Supported by the National Natural Sciences Foundation of China(81471325);Supported by the National Natural Sciences Foundation of China(31430048);Supported by the National Natural Sciences Foundation of China(81625008)

Abstract:

Objective To investigate the role of OpenBCI module in the electroencephalographic (EEG) detection of epileptic discharge.Methods C57BL/6J mice aged 8-12 weeks were divided into two groups:the sham-operated group and kainic acid-induced epileptic group. Spontaneous seizures were monitored continuously for 3 weeks either by EEG or by OpenBCI.Results Up to 8 mice could be simultaneously monitored by OpenBCI. Meanwhile,the module accurately recorded the resting discharge,EEG spikes,and seizures.Conclusion Compared with the conventional brain function monitoring system,the OpenBCI module has lower cost and data occupancy and thus may be applied in clinical settings.

Key words: seizures, kainic acid, electroencephalogram

CLC Number: