Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2019, Vol. 41 ›› Issue (5): 678-684.doi: 10.3881/j.issn.1000-503X.10870

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Advances in Autoantibodies against C-reactive Protein in Systemic Lupus Erythematosus

LI Qiuyu1,YU Feng2()   

  1. 1 Department of Respiratory and Critical Care Medicine,Peking University Third Hospital,Beijing 100191,China
    2 Department of Nephrology,Peking University First Hospital,Beijing 100031,China
  • Received:2018-09-23 Online:2019-10-30 Published:2019-11-08
  • Contact: Feng YU
  • Supported by:
    Supported by the National Natural Sciences Foundation of China(81900641);the Medjaden Academy & Research Foundation for Young Scientists MJR(20180030)


Systemic lupus erythematosus(SLE)is a chronic autoimmune disease that involves multiple organs and tissues.Its pathogenic mechanism remains unclear.Impaired inflammatory response and reduced clearance of immune cells are key events in the development of SLE,during which the pentraxin family plays an important role.This article summarizes recent advances in the relationship between anti-C-reactive protein autoantibody and SLE.

Key words: systemic lupus erythematosus, lupus nephritis, autoimmune, apoptosis, anti-C-reactive protein autoantibody

CLC Number: