Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2010, Vol. 32 ›› Issue (3): 340-342.doi: 10.3881/j.issn.1000-503X.2010.03.022

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Effect of Micronutrients on the Immune Status of Human Immunodeficiency Virus-positive Individuals

ZHAO Fei1,FENG Xue-ling2,XU Wei2,MA Yan-Min1,WANG Zhe1,LI Wen-jie3   

  1. 1Institute of STD and AIDS Prevention,Henan Center for Disease Control and Prevention,Zhengzhou 450016,China;2Department of AIDS Prevention,Huaiyang Center For Disease Control and Prevention,Zhoukou,Henan 466700,China;3Department of Nutrition and Food Hygiene,College of Public Health,Zhengzhou University,Zhengzhou 450001,China
  • Received:2009-12-24 Online:2010-06-30 Published:2010-09-10
  • Contact: ZHAO Fei Tel/Fax:0371-68089113,E-mail:zhaofeicute@yahoo.com.cn

Abstract: Objective To evaluate the effect of micronutrients on the immune status of human immunodeficiency virus (HIV)-positive individuals. Methods Totally 102 HIV-positive individuals were randomly divided into supplementation group (received micronutrients supplement) and control group (received placebo). Physical examinations were performed at baseline and at the end of the trial. Immune status were determined in both two groups. Results Age,height,weight,and sex ratio were not significantly different between two groups (all P>0.05). Baseline CD3+,CD4+,and CD8+ T lymphocytes and IgA,IgG,IgM,C3 levels were not significantly different between two groups (all P>0.05),while the levels of CD3+,CD4+,and CD8+ T lymphocytes and IgA,IgG,IgM,C3 were significantly higher in supplementation group than in control group(all P<0.05). Conclusion Supplementation of micronutrients can improve the immune status of HIV-positives individuals.

Key words: human immunodeficiency virus, micronutrients, immune status

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