Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2011, Vol. 33 ›› Issue (4): 473-477.doi: 10.3881/j.issn.1000-503X.2011.04.025

Previous Articles    

Subcutaneous Implanted System for the Treatment of Type 2 Diabetes

LI Yan, GUO Hui   

  1. Department of Endocrinology, Second Division, The First Hospital of Jilin University, Changchun 130031, China
  • Received:2010-08-30 Revised:2011-09-05 Online:2011-08-01 Published:2011-08-01
  • Contact: GUO Hui

Abstract: Type 2 diabetes is a complex metabolic disorder characterized by hyperglycemia arising from a combination of insufficient insulin secretion and resistance to insulin action. Insulin has become an important agent in treating this disease, but long-term administration of insulin not only brings pain and inconvenience to the patients but also causes local adipose tissue atrophy and scleroma. Therefore, novel delivery method has become a hot topic, mainly including improving delivery systems, developing new recombinant insulin, and changing the route of administration. This article introduces DUROS (an implanted delivery system), a new route of drug administration.

Key words: diabetes, insulin, human glucagon-like peptide-1, subcutaneous implanted system

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