Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2011, Vol. 33 ›› Issue (6): 696-700.doi: 10.3881/j.issn.1000-503X.2011.06.022

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Osmotic Demyelination Syndrome in Patients with Hyponatremia Caused by Neurologic Disorders

JIANG Yi, WEI Jun-ji, WANG Ren-zhi, REN Zu-yuan   

  1. Department of Neurosurgery,PUMC Hospital,CAMS and PUMC, Beijing 100730,China
  • Received:2011-10-08 Revised:2012-01-04 Online:2011-12-20 Published:2011-12-20
  • Contact: WEI Jun-ji

Abstract: Hyponatremia is relatively common in patients with neurologic diorders, while its diagnosis and treatment remain controversial. Osmotic demyelination syndrome (ODS) has shown to be closely associated with hyponatremia. ODS patients often present as central pontine myelinolysis, extrapontine myelinolysis, or both. This article reviews the clinical manifestations, pathogenesis, and risk factors of ODS in patients with hyponatremia caused by neurologic disorders.

Key words: neurologic disorder, hyponatremia, osmotic demyelination syndrome, pathogenesis, treatment

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