Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2012, Vol. 34 ›› Issue (1): 41-45.doi: 10.3881/j.issn.1000-503X.2012.01.008

• Original Articles • Previous Articles     Next Articles

Clinical and Imaging Manifestations of PulmonaryMucosa-associated Lymphoid Tissue Lymphoma

SUI Xin1,SONG Wei1,JIN Zheng-yu1,FENG Rui-e2, CUI Quan-cai2,XUE Hua-dan1,LI Shuo1,SUN Hao1   

  1. 1Department of Radiology, 2Department of Pathology, PUMC Hospital,PUMC and CAMS,Beijing 100730,China
  • Received:2011-06-07 Revised:2012-03-02 Online:2012-03-01 Published:2012-03-01

Abstract: Objective To investigate the clinical and computed tomography (CT) appearances of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma. Methods The CT findings and clinical data of 13 patients with pathologically proven pulmonary MALT lymphoma were retrospectively reviewed. Results Among these 13 patients, seven presented no notable abnormalities, six manifested respiratory symptoms including cough, expectoration, and dyspnea; one of these six patients experienced fever. Chest CT showed solitary nodule in 2 patients and multiple nodules in 3 patients; meanwhile, it showed solitary consolidation in 3 patients and multiple consolidations in 5 patients. Other CT findings included air bronchogram (n=13), airway dilatation (n=4), ground glass opacities (n=5), and interstitial changes (n=5). One patient had mediastinal lymphoadenopathy and 2 had pleural effusion. Pathology showed massive lymphocyte infiltration; cells with notable nuclear atypia were also seen, which were generated from B cells. Conclusions The main CT findings of pulmonary MALT lymphoma include nodules, mass or patchy consolidations with air brochogram; hilar and mediastinal lymphadenopathies are rare. Clinical diagnosis should also be based on pathological findings and immunohistochemical results.

Key words: lung neoplasm, lymphoma, X-ray computed tomography

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