Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2012, Vol. 34 ›› Issue (1): 51-57.doi: 10.3881/j.issn.1000-503X.2012.01.010

• Original Articles • Previous Articles     Next Articles

An Experimental Study on Rabbit Liver by 3.0 Tesla MagneticResonance Diffusion-weighted Imaging

DONG Tian-ming1, SUN Xi-jie2, XU Xian1, DAI Jing3, ZHENG Wei4, AN Ning-yu1, WANG Xiao-qing5   

  1. 1Department of Radiology,3Department of Animal Experimental Center, Chinese PLA General Hospital, Beijing 100853, China;2Department of Radiology, Chinese PLA Navy General Hospital, Beijing 100048, China;4Department of Radiology, 261st Hospital of Chinese PLA, Beijing 100094, China;5Medical Team of 95820 Troops, Beijing 102207, China
  • Received:2011-08-22 Revised:2012-03-02 Online:2012-03-01 Published:2012-03-01

Abstract: Objective To explore the methodology as well as the features, quantificational index, and reference standard of 3.0 Tesla magnetic resonance (MR) diffusion-weighted imaging (DWI) on the normal rabbits liver. Methods Twenty New Zealand white rabbits were enrolled and DWI was performed after anesthetics with multi-b values at 3.0T MR scanner. Apparent diffusion coefficient (ADC) values as well as the difference between maximum and minimum ADC values, signal strength (SH), noise signal (SD), signal to noise ratio (SNR), and quality index (QI) were recorded and analyzed. Results With b value increased, the ADC values decreased accordingly (P0.05). The SD decreased at the same time (P0.05). The SNR decreased at the same time (P0.05). The SNR of DWI with b=800 s/mm2 and b=1000 s/mm2 was lower. The QI decreased at the same time (P0.05). Conclusion When 3.0T MR DWI is applied for rabbit liver, it is better to use b=600 s/mm2 for reducing scanning time and assuring better diffusion weights, quantity of images, and stability of ADC measurement.

Key words: liver, magnetic resonance imaging, diffusion-weighted imaging, animal experiment

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