Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2013, Vol. 35 ›› Issue (3): 348-352.doi: 10.3881/j.issn.1000-503X.2013.03.020

• Orignal Article • Previous Articles     Next Articles

Validity of Complex Figure Test in Differentiation of Alzheimer’s Disease from Non-dementia

HONG Xia1,ZHANG Zhen-xin2,WU Li-yong3,SHI Li-li1,ZHAO Xiao-hui1,WEI Jing1   

  1. 1Department of Psychological Medicine,2Department of Neurology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
       3Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China
  • Received:2013-01-14 Online:2013-07-04 Published:2013-07-04
  • Contact: WEI Jing Tel:010-69156066,


Objective To assess the validity of Complex Figure Test(CFT)in differentiating Alzheimer’s disease(AD)from non-dementia.Methods Using CFT,we tested 183 AD patients(AD group),1283 cognitively intact individuals(normal control group),and 134 individuals suffered from other diseases that could be easily confused with dementia(confused control group).Results The CFT score was 38.7±0.2 in the normal control group,35.3±0.8 in confused control group,23.7±0.8 in mild AD group,and 13.2±1.1 in moderate AD group after adjusted for educational level,age,and sex(all P<0.05).With the 5th percentage of the overall score as cutoff point,this tool showed a sensitivity of 73.8% and a specificity of 93.8% in differentiating AD from non-dementia.Conclusion CFT is a sensitive and specific tool in the differentiation of AD from non-dementia.

Key words: dementia, Alzheimer’s disease, neuropsychological test, Complex Figure Test

CLC Number: