Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2014, Vol. 36 ›› Issue (4): 377-384.doi: 10.3881/j.issn.1000-503X.2014.04.006

• Original article • Previous Articles     Next Articles

Comparison of 3D Pseudo-continuous Arterial Spin Labeling and Positron Emission Tomography-computed Tomography in the Brain Disorders

CHEN Zhi-ye1,GUAN Zhi-wei2,YU Sheng-yuan3,MA Lin1   

  1. 1Department of Radiology,2Departmeng of Nuclear Medicine,3Departmeng of Neurology,Chinese PLA General Hospital,Beijing 100853,China
  • Received:2014-01-20 Online:2014-08-31 Published:2014-08-31
  • Contact: MA Lin Tel:010-66939592,E-mail:cjr.malin@vip.163.com

Abstract: Objective To evaluate the diagnostic agreement of 3D pseudo-continuous arterial spin labeling (3D-pCASL) and 18F-fluorodeoxyglucose and 11C-Methionine positron emission tomography-computed tomography(PET/CT) for brain disorders. Method 3D-pCASL and PET/CT were performed on 7 patients with different brain disorders,and the diagnostic agreement was assessed by visual observation. Results Four tumor lesions presented hyperperfusion on 3D-pCASL,and hypermetabolism on PET/CT. One demyelinated lesion and one metabolic lesion showed hyperperfusion on 3D-pCASL,and one infected lesion showed hypoperfusion on 3D-pCASL;all these three lesions showed hypermetabolism on PET/CT. Conclusion 3D-pCASL can non-invasively evaluate the perfusion state of the brain disorder in vivo and have a good dignostic consistency with PET/CT.

Key words: arterial spin labeling, perfusion weighted imaging, positron emission tomography-computed tomography

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