Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2015, Vol. 37 ›› Issue (5): 602-606.doi: 10.3881/j.issn.1000-503X.2015.05.019

• Orginal Article • Previous Articles     Next Articles

Features of Acquired Immunodeficiency Syndrome-related Lymphoma on 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography

Na NIU(), Zhao-hui ZHU, Yan-ru MA, Hai-qun XING, Fang LI   

  1. Department of Nuclear Medicine,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
  • Received:2014-12-15 Online:2015-10-15 Published:2015-10-31

Abstract:

Objective To analyze the imaging features of 18F-fluorodeoxyglucose(18F-FDG) positron emission tomography(PET)/computed tomography(CT) in acquired immune deficiency syndrome-related lymphoma(ARL) patients correlated with their clinical signs,symptoms,and treatments.Methods Five ARL patients underwent 18F-FDG PET/CT at Peking Union Medical College Hospital from October 2008 to January 2013. Two patients received two additional follow-up studies 6 months later. Results Among these 5 patients,18FDG-PET/CT helped in diagnosis of two patient and changed therapeutic strategy in other two patients. In two patients underwent 18F-FDG PET/CT brain scans,low-metabolism lesion was newly found in cerebral cortex. Of 4 patients receiving highly active antiretroviral therapy,PET/CT also demonstrated diffusely elevated 18F-FDG uptake in subcutaneous adipose tissue in two patients. Conclusion 18F-FDG PET/CT is a highly useful tool in the diagnosis and treatment of ARL patients,in particular in the identification of associated encephalopathy and lipodystrophy.

Key words: acquired immunodeficiency syndrome-related lymphoma, highly active anti-retroviral therapy, positron emission tomography/computed tomography, fluorodeoxyglucose

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