Acta Academiae Medicinae Sinica ›› 2016, Vol. 38 ›› Issue (5): 601-606.doi: 10.3881/j.issn.1000-503X.2016.05.020
• Orginal Article • Previous Articles Next Articles
Received:
2015-09-06
Online:
2016-10-20
Published:
2016-10-10
Supported by:
CLC Number:
Qing SUN, Xiao-chun LIANG. Advances in the Relationship between Adipokines and β-cell Failure in Type 2 Diabetes Mellitus[J].Acta Academiae Medicinae Sinica, 2016, 38(5): 601-606.
[1] | Leahy JL,Hirsch IB,Peterson KA,et al.Targeting beta-cell function early in the course of therapy for type 2 diabetes mellitus[J]. J Clin Endocrinol Metab,2010,95(9):4206-4216. |
[2] | Chang-Chen KJ,Mullur R,Bernal-Mizrachi E,et al.Beta-cell failure as a complication of diabetes[J]. Rev Endocr Metab Disord,2008,9(4):329-343. |
[3] | Jonas JC,Bensellam M,Duprez J,et al.Glucose regulation of islet stress responses and beta-cell failure in type 2 diabetes[J]. Diabetes Obes Metab,2009,11(Suppl 4):65-81. |
[4] | Weir GC,Laybutt DR,Kaneto H,et al.Beta-cell adaptation and decompensation during the progression of diabetes[J]. Diabetes,2001,50(Suppl 1):S154-S159. |
[5] | Deng Y,Scherer PE.Adipokines as novel biomarkers and regulators of the metabolic syndrome[J]. Ann N Y Acad Sci,2010,1212:E1-E19. |
[6] | Wellen KE,Hotamisligil GS.Inflammation,stress,and diabetes[J]. J Clin Invest,2005,115(5):1111-1119. |
[7] | Zhang Y,Proenca R,Maffei M,et al.Positional cloning of the mouse obese gene and its human homologue[J].Nature,1994,372(6505):425-432. |
[8] | Ahrénn B,Larsson H.Leptin-a regulator of islet function: its plasma levels correlate with glucagon and insulin secretion in healthy women[J]. Metabolism,1997,46(12):1477-1481. |
[9] | Laubner K,Kieffer TJ,Lam NT,et al.Inhibition of preproinsulin gene expression by leptin induction of suppressor of cytokine signaling 3 in pancreatic beta-cells[J]. Diabetes,2005,54(12):3410-3417. |
[10] | Brown JE,Thomas S,Digby JE,et al.Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets[J]. FEBS Lett,2002,513(2-3):189-192. |
[11] | Brown JE,Onyango DJ,Dunmore SJ.Resistin down-regulates insulin receptor expression,and modulates cell viability in rodent pancreatic beta-cells[J]. FEBS Lett,2007,581(17):3273-3276. |
[12] | Chetboun M,Abitbol G,Rozenberg K,et al.Maintenance of redox state and pancreatic beta-cell function: role of leptin and adiponectin[J]. J Cell Biochem,2012,113(6):1966-1976. |
[13] | Ning K,Miller LC,Laidlaw HA,et al.A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells[J]. EMBO J,2006,25(11):2377-2387. |
[14] | Wang L,Liu Y,Yan Lu S,et al.Deletion of Pten in pancreatic β-cells protects against deficient β-cell mass and function in mouse models of type 2 diabetes[J].Diabetes,2010,59(12):3117-3126. |
[15] | Scherer PE,Williams S,Fogliano M,et al.A novel serum protein similar to C1q,produced exclusively in adipocytes[J]. J Biol Chem,1995,270(45): 26746-26749. |
[16] | Arita Y,Kihara S,Ouchi N,et al.Paradoxical decrease of an adipose-specific protein,adiponectin,in obesity[J]. Biochem Biophys Res Commun,1999,257(1):79-83. |
[17] | Pajvani UB,Du X,Combs TP,et al.Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity[J].J Biol Chem,2003,278(11):9073-9085. |
[18] | Ouchi N,Kihara S,Arita Y,et al.Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin[J]. Circulation,1999,100(25):2473-2476. |
[19] | Kadowaki T,Yamauchi T.Adiponectin and adiponectin receptors[J]. Endocr Rev,2005,26(3):439-451. |
[20] | Kharroubi I,Rasschaert J,Eizirik DL,et al.Expression of adiponectin receptors in pancreatic beta cells[J]. Biochem Biophys Res Commun,2003,312(4): 1118-1122. |
[21] | Brown JE,Conner AC,Digby JE,et al.Regulation of beta-cell viability and gene expression by distinct agonist fragments of adiponectin[J]. Peptides,2010,31(5):944-949. |
[22] | Wijesekara N,Krishnamurthy M,Bhattacharjee A,et al.Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion[J]. J Biol Chem,2010,285(44): 33623-33631. |
[23] | Jung TW,Lee MW,Lee YJ,et al.Regulation of adiponectin receptor 2 expression via PPAR-alpha in NIT-1 cells[J]. Endocr J,2009,56(3):377-382. |
[24] | Lin P,Chen L,Li D,et al.Adiponectin reduces glucotoxicity-induced apoptosis of INS-1 rat insulin-secreting cells on a microfluidic chip[J]. Tohoku J Exp Med,2009,217(1):59-65. |
[25] | Hotamisligil GS.Mechanisms of TNF-alpha-induced insulin resistance[J]. Exp Clin Endocrinol Diabetes,1999,107(2):119-125. |
[26] | Zhao YF,Feng DD,Chen C.Contribution of adipocyte-derived factors to beta-cell dysfunction in diabetes[J]. Int J Biochem Cell Biol,2006,38(5-6): 804-819. |
[27] | Ortis F,Pirot P,Naamane N,et al.Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells[J]. Diabetologia,2008,51(7):1213-1225. |
[28] | Ortis F,Miani M,Colli ML,et al.Differential usage of NF-κB activating signals by IL-1β and TNF-α in pancreatic beta cells[J]. FEBS Lett,2012,586(7): 984-989. |
[29] | Kim HE,Choi SE,Lee SJ,et al.Tumour necrosis factor-alpha-induced glucose-stimulated insulin secretion inhibition in INS-1 cells is ascribed to a reduction of the glucose-stimulated Ca2+ influx[J]. J Endocrinol,2008,198(3): 549-560. |
[30] | Cai K,Qi D,Wang O,et al.TNF-alpha acutely upregulates amylin expression in murine pancreatic beta cells[J]. Diabetologia,2011,54(3):617-626. |
[31] | Westermark P,Andersson A,Westermark GT.Islet amyloid polypeptide,islet amyloid,and diabetes mellitus[J]. Physiol Rev,2011,91(3):795-826. |
[32] | Steppan CM,Bailey ST,Bhat S,et al.The hormone resistin links obesity to diabetes[J]. Nature,2001,409(6818): 307-312. |
[33] | Nagaev I,Smith U.Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle[J]. Biochem Biophys Res Commun,2001,285(2):561-564. |
[34] | Nakata M,Okada T,Ozawa K,et al.Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release[J]. Biochem Biophys Res Commun,2007,353(4):1046-1051. |
[35] | Minn AH,Patterson NB,Pack S,et al.Resistin is expressed in pancreatic islets[J]. Biochem Biophys Res Commun,2003,310(2):641-645. |
[36] | Al-Salam S,Rashed H,Adeghate E.Diabetes mellitus is associated with an increased expression of resistin in human pancreatic islet cells[J]. Islets,2011,3(5):246-249. |
[37] | Fukuhara A,Matsuda M,Nishizawa M,et al.Visfatin: a protein secreted by visceral fat that mimics the effects of insulin[J]. Science,2005,307(5708): 426-430. |
[38] | Revollo JR,Körner A,Mills KF,et al.Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme[J]. Cell Metab,2007,6(5):363-375. |
[39] | Brown JE,Onyango DJ,Ramanjaneya M,et al.Visfatin regulates insulin secretion,insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells[J]. J Mol Endocrinol,2010,44(3):171-178. |
[40] | Cheng Q,Dong W,Qian L,et al.Visfatin inhibits apoptosis of pancreatic β-cell line,MIN6,via the mitogen-activated protein kinase/phosphoinositide 3-kinase pathway[J]. J Mol Endocrinol,2011,47(1):13-21. |
[41] | 盛飞凤,任贤,戴幸平,等.烟酰胺单核苷酸对RIN-m5f细胞中胰岛素分泌及PDX-1和FoxO1基因表达的影响[J].中南大学学报:医学版,2011,36(10):958-963. |
[42] | Kazafeos K.Incretin effect: GLP-1,GIP,DPP4[J]. Diabetes Res Clin Pract,2011,93(Suppl 1):S32-S36. |
[43] | Buteau J.GLP-1 receptor signaling: effects on pancreatic beta-cell proliferation and survival[J]. Diabetes Metab,2008,34(Suppl 2):S73-S77. |
[44] | Lamers D,Famulla S,Wronkowitz N,et al.Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome[J]. Diabetes,2011,60(7):1917-1925. |
[45] | Sell H,Blüher M,Klöting N,et al.Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro[J]. Diabetes Care,2013,36(12):4083-4090. |
[46] | Sörhede Winzell M,Magnusson C,Ahrén B.The apj receptor is expressed in pancreatic islets and its ligand,apelin,inhibits insulin secretion in mice[J]. Regul Pept,2005,131(1-3):12-17. |
[47] | Guo L,Li Q,Wang W,et al.Apelin inhibits insulin secretion in pancreatic beta-cells by activation of PI3-kinase-phosphodiesterase 3B[J]. Endocr Res,2009,34(4):142-154. |
[48] | Han S,Englander EW,Gomez GA,et al.Pancreatic islet APJ deletion reduces islet density and glucose tolerance in mice[J]. Endocrinology,2015,156(7): 2451-2460. |
[49] | Chen H,Zheng C,Zhang X,et al.Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice[J].Peptides,2011,32(8):1634-1639. |
[50] | Ringström C,Nitert MD,Bennet H,et al.Apelin is a novel islet peptide[J]. Regul Pept,2010,162(1-3):44-51. |
[1] | NAN Min, LI Wenhui. Role of Paradoxical Hypersecretion of Glucagon in the Pathogenesis of Type 2 Diabetes Mellitus [J]. Acta Academiae Medicinae Sinica, 2018, 40(3): 421-426. |
[2] | Fangfang XU, Nan WANG, Gangqiang LI, Wenfang GUO, Caifeng YANG, Dehu LIU. Establishment and Assessment of Mice Models of Type 2 Diabetes Mellitus [J]. Acta Academiae Medicinae Sinica, 2017, 39(3): 324-329. |
[3] | Chao JIANG, Da-peng LI, Zhi-jian ZHANG, Hao-ming SHU, Lang HU, Zheng-nan LI, Yong-hui HUANG. Effect of Basic Fibroblast Growth Factor and Transforming Growth Factor-β1 Combined with Bone Marrow Mesenchymal Stem Cells on the Repair of Degenerated Intervertebral Discs in Rat Models [J]. Acta Academiae Medicinae Sinica, 2015, 37(4): 456-465. |
[4] | Tao YUAN, Juan LI, Wei-gang ZHAO, Yong FU, Shuai-nan LIU, Quan LIU, Zhu-fang SHEN. Effects of Estrogen on Insulin Sensitivity and Adipokines in Mice [J]. Acta Academiae Medicinae Sinica, 2015, 37(3): 269-273. |
[5] | YANG Lu,SONG Mei-qing,ZHANG Qiu-ling,SHOU Lan,ZANG Shu-fei,YANG Yan-li. Effect of Piglitazone and Metformin on Retinol-binding Protein-4 and Adiponcetin in Patients with Type 2 Diabetes Mellitus Complicated with Non-alcohol Fatty Acid Liver Diseases [J]. Acta Academiae Medicinae Sinica, 2014, 36(3): 309-312. |
[6] | HAN Rui-mei,LI Nan-fang,YAN Zhi-tao,GUO Yan-ying,ZHANG Ju-hong,WANG Hong-mei,HONG Jing,ZHOU Ling. Genetic Polymorphism of Six Transmembrance Protein of Prostate 2 Associated with Diabetes Mellitus in Xinjiang Uygur Population [J]. Acta Academiae Medicinae Sinica, 2012, 34(5): 509-514. |
[7] | ZHANG Qiu-ling, ZANG Shu-fei. Correlation of T Lymphocyte Subsets with Blood Glucose Level and the First-Phase Insulin Secretion in Patients with Type 2 Diabetes Mellitus [J]. Acta Academiae Medicinae Sinica, 2012, 34(3): 254-257. |
[8] | CHANG Cui-qing. Individualized Exercise Training Prescription for Patients with Type 2 Diabetes Mellitus [J]. Acta Academiae Medicinae Sinica, 2011, 33(3): 248-252. |
[9] | MIN Rui, LI Yu-xiu. Comprehensive Treatment for Type 2 Diabetes Mellitus [J]. Acta Academiae Medicinae Sinica, 2011, 33(3): 257-261. |
[10] | HUANG Chih-kun. Effectiveness and Safety of Laparoscopic Roux-en-Y Gastric Bypass in Treating Type 2 Diabetes Mellitus in Non-morbidly Obese Patients [J]. Acta Academiae Medicinae Sinica, 2011, 33(3): 272-276. |
[11] | LI Wen-hui;XIAO Xin-hua;YU Kang;SUN Qi;YANG Guo-hua;WANG Heng;Ole Schmitz. Influence of Short-term High-fat Diet on Glucose and Lipid Metabolism in Male Han Chinese with Type 2 Diabetes Mellitus [J]. Acta Academiae Medicinae Sinica, 2008, 30(4): 509-515. |
[12] | LI Yan, HUANG Bin, CHENG Hua, LIANG Zhen, LIU Shan-ying. Effect of Peroxisome Proliferator-Activated Receptor-α Agonist on Adipokines Expression in Rats Fed with High-fat Diet [J]. Acta Academiae Medicinae Sinica, 2006, 28(6): 761-765. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||
|