Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2017, Vol. 39 ›› Issue (5): 629-636.doi: 10.3881/j.issn.1000-503X.2017.05.006

• Orginal Article • Previous Articles     Next Articles

Polymorphisms of 23 Y-chromosome STR Loci in A Han Population in Jiangsu Province

Jun MA1, Aihua ZHU1, Jinwei SHI1, Ming JIN1, Huajie BA1, Zhiguang PING2()   

  1. 1Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China
    2Department of Health Biostatistics,College of Public Health,Zhengzhou University,Zhengzhou 450001,China
  • Received:2016-07-14 Online:2017-10-30 Published:2017-10-30

Abstract:

Objective To investigate the polymorphisms of 23 Y-STR loci in a Han population in Jiangsu province. Methods Blood samples were collected from 4821 unrelated healthy Han males in Jiangsu province. DNA templates were amplified by PowerPlex Y23 kit,and the amplification products were detected by 3500xL genetic analyzer. Then,we calculated the allele frequencies and gene diversities respectively,as well as the haplotype frequencies and haplotype diversities. Results The gene diversity of these 23 Y-STR loci ranged 0.4099-0.9696. A total of 4781 haplotypes were detected,of which 4743 were found once. The haplotype diversity was 0.99999812. Conclusion The 23 Y-STR loci used in this study are highly polymorphic in Han individuals in Jiangsu province and therefore suitable for population genetic study and forensic individual identification.

Key words: Y chromosome, short tandem repeat, genetic polymorphism

CLC Number: