Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (2): 187-193.doi: 10.3881/j.issn.1000-503X.2018.02.008
• Original Articles • Previous Articles Next Articles
WANG Botao1, HE Lei1, LIU Gang2, LIU Mengqi1, 2, CHEN Zhiye1, 2()
Received:
2017-07-25
Online:
2018-04-28
Published:
2018-05-03
About author:
The first two author contributed equally to this article
CLC Number:
WANG Botao, HE Lei, LIU Gang, LIU Mengqi, CHEN Zhiye. Value of Magnetic Resonance Imaging Texture Feature Analysis in the Differential Diagnosis between Pancreatic Serous Cystadenoma and Mucinous Cystadenoma[J].Acta Academiae Medicinae Sinica, 2018, 40(2): 187-193.
Table 1
Comparisons of demographic and clinicopathological features between 24 patients with serous cystadenoma and 20 patients with mucinous cystadenoma"
分组Group | 女/男a Female/malea(n) | 年龄( Age( | 肿瘤直径[中位数 (四分位数间距),cm]b Tumor size [median(QR),cm]b | 单囊型/多囊型a Single cystic/ Polycystic a (n) | 胰腺头颈/体尾部a Head and neck of pancreas/ body and tail of pancreas a (n) |
---|---|---|---|---|---|
浆液性囊腺瘤 Serous cystadenoma(n=24) | 19/5 | 51.9±14.4 | 2.8(1.8) | 5/19 | 12/12 |
黏液性囊腺瘤 Mucinous cystadenoma(n=20) | 15/5 | 49.1± 8.5 | 3.6(1.7) | 6/14 | 6/14 |
χ2/U | 0.108 | 0.809 | 142.500 | 0.122 | 1.072 |
P | 0.743 | 0.423 | 0.021 | 0.727 | 0.300 |
Table 2
Comparisons of five texture parameters of T1WI between 24 patients with serous cystadenoma and 20 patients with mucinous cystadenoma"
分组Group | 角二阶矩 [中位数(四分位数间距)] a Angular second moment [median(QR)] a | 对比度[中位数 (四分位数间距)] a Contrast [median(QR)] a | 自相关 [中位数(四分位数间距)] a Correlation[median(QR)] a | 逆差距 Inverse difference moment( | 熵Entropy ( |
---|---|---|---|---|---|
浆液性囊腺瘤 Serous cystadenoma (n=24) | 0.006(0.010) | 37.411(53.260) | 0.006(0.020) | 0.252±0.087 | 5.155±0.817 |
黏液性囊腺瘤 Mucinous cystadenoma (n=20) | 0.008(0.010) | 13.219(25.710) | 0.017(0.020) | 0.342±0.112 | 5.204±0.520 |
U/t | 224.500 | 115.000 | 163.000 | 3.025 | 0.231 |
P | 0.714 | 0.003 | 0.069 | 0.004 | 0.818 |
95% CI | 0.007~0.012 | 24.457~45.922 | 0.011~0.019 | 0.260~-0.326 | 4.968~5.388 |
Table 3
Receiver operating characteristic curve analysis of the texture contrast,correlation,inverse difference moment, and the model of Logistic regression between serous and mucinous cystadenoma"
参数Parameter | 曲线下面积 Area under curve | 临界值 Critical value | 95% CI | 敏感性 Sensitivity | 特异性 Specificity | 临界值以上 Above critical value | 临界值以下 Below critical value |
---|---|---|---|---|---|---|---|
T2WI | |||||||
对比度Contrast | 0.846 | 40.891 | 58.284-108.299 | 0.800 | 0.875 | 浆液性囊腺瘤 Serous cystadenoma | 黏液性囊腺瘤 Mucinous cystadenoma |
自相关Correlation | 0.821 | 0.008 | 0.000- 0.136 | 0.550 | 0.917 | 黏液性囊腺瘤 Mucinous cystadenoma | 浆液性囊腺瘤 Serous cystadenoma |
逆差距 Inverse difference moment | 0.746 | 0.248 | 0.306- 0.460 | 0.900 | 0.708 | 黏液性囊腺瘤 Mucinous cystadenoma | 浆液性囊腺瘤 Serous cystadenoma |
T1WI | |||||||
对比度Contrast | 0.760 | 13.578 | 25.097- 48.200 | 0.550 | 0.917 | 浆液性囊腺瘤 Serous cystadenoma | 黏液性囊腺瘤 Mucinous cystadenoma |
逆差距 Inverse difference moment | 0.736 | 0.317 | 0.252- 0.350 | 0.650 | 0.792 | 黏液性囊腺瘤 Mucinous cystadenoma | 浆液性囊腺瘤 Serous cystadenoma |
Logistic回归模型 Model of Logistic regression | 0.879 | - | 0.359- 0.554 | 0.900 | 0.792 | - | - |
Table 4
Comparisons of five texture parameters of T2WI between 24 patients with serous cystadenoma and 20 patients with mucinous cystadenoma"
分组Group | 角二阶矩[中位数 (四分位数间距)]a Angular second moment [median(QR)] a | 对比度[中位数 (四分位数间距)]a Contrast [median(QR)] a | 自相关[中位数 (四分位数间距)]a Correlation [median(QR)] a | 逆差距 Inverse difference moment( | 熵[中位数 (四分位数间距)]a Entropy [median(QR)] a |
---|---|---|---|---|---|
浆液性囊腺瘤 Serous cystadenoma(n=24) | 0.005(0.010) | 114.194(98.540) | 0.002(0.000) | 0.297±0.248 | 5.714(1.420) |
黏液性囊腺瘤 Mucinous cystadenoma(n=20) | 0.008(0.030) | 14.714(25.320) | 0.009(0.040) | 0.456±0.192 | 5.320(1.720) |
U/t | 174.500 | 74.000 | 86.000 | 2.345 | 166.000 |
P | 0.122 | 0.000 | 0.000 | 0.024 | 0.081 |
95% CI | 0.024~0.135 | 57.201~106.150 | 0.006~-0.021 | 0.300~-0.441 | 4.346~5.323 |
Fig 2
Two lesions on the pancreatic body presented hypointensity on T1WI and hyperintensity on T2WI(A and C,T2WI;B and D,T1WI);the texture parameters were placed into the model of Logistic regression,and the result suggested that the first lesion(A,B) could be considered as mucious cystadenoma and the second lesion(C,D) as serous cystadenoma,which were consistent with the pathologic diagnoses"
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