Acta Academiae Medicinae Sinica

Abstract:

Objective To investigate the difference of tumor textures presented on T1-weighted image(T1WI) and T2-weighted image(T2WI) between pancreatic serous cystadenoma and mucinous cystadenoma. Methods Subjects including 24 patients with serous cystadenoma and 20 patients with mucinous cystadenoma who were treated in Hainan Branch of Chinese PLA General Hospital were enrolled in this study.The texture analysis was performed on T1WI and T2WI,and the texture parameters included angular second moment,contrast,correlation,inverse difference moment(IDM),and entropy.Independent sample t-test and Mann-Whitney U test were performed for the between-group comparison,the regression model was established by Binary Logistic regression analysis,and receiver operating characteristics curve(ROC) was drawn.Results The contrast and IDM of T1WI and the contrast,correlation,and IDM of T2WI showed significant differences between serous cystadenoma and mucinous cystadenoma(T1WI∶\begin{array}{c}{{{{P_{\mathit{angular}}}_{}}_{\mathit{second}}}_{}}_{\mathit{moment}}\end{array}=0.714,P_contrast=0.003,P_correlation=0.069,P_IDM=0.004,P_entropy=0.818;T2WI∶\begin{array}{c}{{{{P_{\mathit{angular}}}_{}}_{\mathit{second}}}_{}}_{\mathit{moment}}\end{array}=0.122,P_contrast=0.000,P_correlation=0.000,P_IDM=0.024,and P_entropy=0.081).The area under the ROC curve was 0.736-0.846 for the positive texture variables,and the area under the ROC curve was 0.879 for the variables in the model of Logistic regression.Binary Logistic regression analysis demonstrated that the contrast was a specific imaging variable for the differential diagnosis between serous cystadenoma and mucinous cystadenoma.Conclusion The texture analysis of T1WI and T2WI may be a simple and effective tool in the differential diagnosis between pancreatic serous cystadenoma and mucinous cystadenoma.

Key words: pancreas, serous cystadenoma, mucinous cystadenoma, texture analysis, magnetic resonance imaging