Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (2): 194-200.doi: 10.3881/j.issn.1000-503X.2018.02.009

• Original Articles • Previous Articles     Next Articles

Interval-spaced Sessions of Partial Splenic Artery Embolization in Juvenile Patients with Hypersplenism

LIU Duan, SHAO Jiang, CHEN Yu, LIU Bao, SONG Xiaojun, CHEN Yuexin, LIU Changwei, YE Wei, ZENG Rong, LIU Zhili, ZHENG Yuehong()   

  1. Department of Vascular Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
  • Received:2017-06-15 Online:2018-04-28 Published:2018-05-03

Abstract:

Objective To determine whether interval-spaced sessions of partial splenic artery embolization(PSE) is a safe and effective alternative treatment for hypersplenism in juvenile patients. Methods Eight patients(3 males and 5 females) were included in this retrospective study.All patients were diagnosed as hypersplenism and underwent PSE in 2-3 sessions separated by 1-2 month intervals.Immediate,short,and long term follow-up were done.The effectiveness of the treatment was evaluated.Results No major postoperative complication was noted.No patient developed septic shock,splenic abscess,or spleen rupture.Postoperative pain and fever were common and manageable;only two patients developed loculated pleural effusions,which were well alleviated after conservative treatment.All patients showed significant increase in thrombocytes and white blood cells count after the first session of embolization.The cell counts became remarkable after the last session and remained at normal levels during the follow-up period.Conclusions PSE using 2-3 interval-spaced sessions can effectively decrease spleen size and reverse hypersplenism in juvenile patients.Also,it may reduce the postoperative complications commonly seen in traditional PSE.

Key words: hypersplenism, partial splenic artery embolization, thrombocytopenia

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