Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (2): 284-288.doi: 10.3881/j.issn.1000-503X.2018.02.021

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Interleukin-6 in Psoriasis

WANG Wenming, JIN Hongzhong()   

  1. Department of Dermatology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
  • Received:2017-03-27 Online:2018-04-28 Published:2018-05-03

Abstract:

Psoriasis is a common,multifactorial,chronic inflammatory skin disease with an incompletely understood pathogenesis. A substantial number of inflammatory cytokines have been found to be elevated in psoriatic lesions,and the serum levels of a subset of these cytokines also correlate with the severity of psoriasis. Interleukin-6 is a multifunctional pro-inflammatory cytokine. Interleukin-6 is proved to be associated with many chronic inflammatory diseases and autoimmunity diseases such as psoriasis. This article reviews the relationship between interleukin-6 and psoriasis.

Key words: interleukin-6, psoriasis, Th17 cells, Treg cells

CLC Number: