Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (3): 328-333.doi: 10.3881/j.issn.1000-503X.2018.03.005

• Original Articles • Previous Articles     Next Articles

Clinical Features and Outcomes of Paraduodenal Pancreatitis

LI Zhuoran1,CAO Di1,LI Juan2,YANG Hong1,HAN Xianlin3,XUE Huadan2,YOU Yan4,ZHOU Weixun4,WU Dong1(),QIAN Jiaming1   

  1. 1 Department of Gastroenterology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China
    2 Department of Radiology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China
    3 Department of General Surgery, PUMC Hospital,CAMS and PUMC,Beijing 100730,China
    4 Department of Pathology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
  • Received:2018-04-10 Online:2018-06-30 Published:2018-07-05
  • Supported by:
    Supported by the Health Research & Special Projects Grant of China(201002020)


Objective To summarize the clinical features and outcomes of paraduodenal pancreatitis (PP).Methods Five clinically or pathologically diagnosed PP patients in Peking Union Medical College Hospital and 31 other PP cases reported in Chinese literature since 1988 were retrospectively analysed.Results Most PP patients were young or middle-aged males with a history of alcohol abuse. The clinical symptoms included upper abdominal pain,vomiting,weight loss,and fluctuating jaundice. Serum pancreatic enzymes were normal or elevated. Radiological features in most cases included thickening of the duodenal wall and duodenal stenosis (88.9%,32/36),cysts in the duodenal wall and groove area (47.2%,17/36),dilated bile duct (36.1%,13/36),and dilated pancreatic duct (16.7%,6/36). The main pathological finding was chronic pancreatitis,which could be accompanied by local acute inflammation,which was limited in the groove-duodenal area in most cases. The disease can be well controlled by conservative treatment,although surgery was needed in a small number of cases.Conclusions PP typically occurs in young or middle-aged males. Radiological examination is valuable for diagnosis. Conservative treatment is the mainstream treatment in most patients.

Key words: paraduodenal pancreatitis, groove pancreatitis, chronic pancreatitis, duodenal wall cyst, endoscopic retrograde cholangiopancreatography

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