Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2018, Vol. 40 ›› Issue (3): 432-435.doi: 10.3881/j.issn.1000-503X.2018.03.024

• Case Reports • Previous Articles     Next Articles

Lynch Syndrome:Report of One Case and Literature Review

GUO Yanping1,WANG Chunbao2,LI Yang1,YANG Xiaofeng1()   

  1. 1 Department of Obstetrics and Gynecology, the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China;
    2 Department of Pathology,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China;
  • Received:2017-11-28 Online:2018-06-30 Published:2018-07-05

Abstract:

This article reports a female type Ⅱ Lynch syndrome patient who suffered from colon cancer and endometrium carcinoma consecutively. We also briefly elucidate the pathogenesis,clinicopathological features,screening,and management of Lynch syndrome. Regular screening and early diagnosis and treatment may help to reduce the incidences and mortality rates of tumors associated with Lynch syndrome.

Key words: Lynch syndrome, mutS homolog 2, endometrium carcinoma, mismatch repair genes

CLC Number: