Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2019, Vol. 41 ›› Issue (1): 129-133.doi: 10.3881/j.issn.1000-503X.10477

• Case Reports • Previous Articles     Next Articles

Wernicke’s Encephalopathy Onset during Diagnosis and Treatment of Peritoneal Mesothelioma:Report of One Case and Literature Review

CHEN Jia1,CHEN Dan2,LI Yue2,SHEN Hang3,LI Ji2(),QIAN Jiaming2   

  1. 1 Department of Internal Medicine, PUMC Hospital,CAMS and PUMC,Beijing 100730,China
    2 Department of Gastroenterology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China
    3 Department of Neurology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
  • Received:2018-04-19 Online:2019-02-28 Published:2019-03-06
  • Contact: Ji LI
  • Supported by:
    Supported by the Education Reform Program of Peking Union Medical College(2017zlgc0110)


Wernicke’s encephalopathy(WE),characterized by nystagmus and ophthalmoplegia,unsteadiness of stance and gait and mental-status changes,is an acute or subacute metabolic encephalopathy of the central nervous system resulting from Vitamin B1(VitB1)deficiency. A 29-year-old male patient was admitted to our hospital due to abdominal pain and fever. He remained chronically undernourished. He was complicated with WE at the late stage of diagnosis,mainly manifested as the convulsion of limbs,ataxia,and delirium. After treatment with VitB1,these neuropsychiatric symptoms were remarkably resolved. His primary disease was later pathologically confirmed as peritoneal mesothelioma.

Key words: Wernicke’s encephalopathy;, vitamin B1, peritoneal mesothelioma

CLC Number: