Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2019, Vol. 41 ›› Issue (5): 630-635.doi: 10.3881/j.issn.1000-503X.10832

• Original Articles • Previous Articles     Next Articles

Correlation between Asymptomatic Bacteriuria and Surgical Site Infection in Middle-aged and Elderly Patients Undergoing Open Hysterectomy

XIE Zhaoyun1(),LI Yaofu1,MENG Guiluan1,XIONG Yun1,LI Yuanjun2,CHEN Yingqiang3   

  1. 1 Department of Infection Management
    2 Department of Obstetrics and Gynecology
    3 Department of Infectious Diseases,the Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou 558000,China
  • Received:2018-09-05 Online:2019-10-30 Published:2019-11-08
  • Contact: Zhaoyun XIE
  • Supported by:
    Supported by the Joint Project of Science and Technology Department of Guizhou Province(Qian Ke he LH )([2014]7162号);the Qiannan Prefecture Social Development Science and Technology Project of Guizhou Province([2015]19号)


Objective To explore the correlation between asymptomatic bacteriuria(AB)and surgical site infection(SSI)in middle-aged and elderly women undergoing open hysterectomy.Methods The clinical data of 1469 middle-aged and elderly women undergoing open hysterectomy in the Third Affiliated Hospital of Guizhou Medical University from June 2011 to August 2018 were retrospectively analyzed.Factors associated with SSI after operation were analyzed by univariate and multivariate regression models to identify the relationship of AB with SSI after open hysterectomy.Results Of these 1469 patients,101(6.88%)had SSI and 124 had AB[including 14 patients(11.29%)with infections].In addition,1345 patients had no AB,among whom 87(6.47%)had infections.Thus,the infection rate in patients with AB was significantly higher than that in patients without AB(χ 2=4.123,P=0.042).Univariate analysis showed AB,history of diabetes mellitus,surgical procedure,length of stay(>15 d),season(summer and autumn),body mass index(≥25 kg/m 2),nature of lesions(malignant tumors),ASA grade(>grade Ⅱ),incision length(≥10 cm),and operative time(≥3 h),bleeding volume(≥1000 ml),serum albumin concentration(<30 g/L),blood glucose(≥10 mmol/L),and hemoglobin concentration(<90 g/L)were associated with SSI(all P <0.05).Multivariate analysis showed that AB,nature of lesions(malignant tumors),blood glucose(≥10 mmol/L),operative time(≥3 h),and ASA grade(>grade Ⅱ)were risk factors for SSI in these patients(all P <0.05). Conclusions AB is one of the risk factors for SSI in middle-aged and elderly women undergoing open hysterectomy.Screening and treatment of AB before surgery can reduce the risk of SSI.ASA grading shall be performed before surgery before corresponding preparation was offered.Effective control of blood glucose,improved surgical skills,and shorter operative time are helpful for lowering postoperative SSI.

Key words: asymptomatic bacteriuria, middle-aged and elderly, hysterectomy, surgical site infection

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