Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2010, Vol. 32 ›› Issue (6): 625-633.doi: 10.3881/j.issn.1000-503X.2010.06.008

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Dual-energy Computed Tomographic Angiography of Head and Neck Arteries with Different Contrast Material Doses in Second GenerationDual-source Computed Tomography System

CHEN Yu, XUE Hua-dan, LIU Wei, SUN Hao, WANG Xuan, SU Bai-yan, SUI Xin, MING Wei-di, DE Jie, QI Bing, LIANG Ji-xiang, JIN Zheng-yu   

  1. Department of Radiology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
  • Received:2010-11-08 Online:2010-12-20 Published:2010-12-20
  • Contact: Corresponding author:JIN Zheng-yu

Abstract: ObjectiveTo explore the feasibility of a dual-energy computed tomographic angiography (DECTA) protocol using test-bolus injection with reduction of contrast material (CM) dose in second generation dual-source CT system. MethodsTotally 57 consecutive patients underwent CT angiography scan covering the cervical and cerebral arteries. CT was performed with second generation dual-source CT system. The time to peak (T) using a test-bolus injection was calculated. The patients were divided into three groups (A, B, and C) with different CM doses (40, 45, and 50 ml) and different delay time points [ (T+1) , (T+1) , and (T+2) s] . All the patients were followed by a 48 ml saline flush. Arterial enhancements were quantified by measuring attenuation values of the aortic arch, bifurcation of common carotid artery, contralateral internal jugular vein of the CM injection, superior vein cava, proximal middle cerebral artery, basilar artery, and straight sinus on source images. Visualizations of intracranial artery and ipsilateral venous effect of the CM injection were rated on a four-point grading scale on CTA images for qualitative assessment. ResultsAlthough the attenuation of internal jugular vein and straight sinus were significantly lower in group A than in groups B and C (P<0.05) , the attenuation of aortic arch, superior vein cava, common carotid artery, middle cerebral artery, and basilar artery vessels showed no significant differences among these three groups. The scores of the visualizations of intracranial artery and ipsilateral venous effect of the CM injection were also not significantly different among these three groups. ConclusionBased on the delay time calculated by a test-bolus injection, a reduced-dose contrast material may provide an equal degree of arterial attenuation and a lower attenuation of vein for dual-engergy CTA covering the craniocervical region in second generation dual-source CT system.

Key words: dual-scoure computed tomography, dual-energy, test-bolus injection, head and neck artery, contrast material

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