Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica

Acta Academiae Medicinae Sinica ›› 2010, Vol. 32 ›› Issue (6): 640-644.doi: 10.3881/j.issn.1000-503X.2010.06.010

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Application of Second Generation Dual-source Computed Tomography Dual-energy Scan Mode in Detecting Pancreatic Adenocarcinoma

XUE Hua-dan, LIU Wei, SUN Hao, WANG Xuan, CHEN Yu, SU Bai-yan, SUN Zhao-yong, CHEN Fang, JIN Zheng-yu   

  1. Department of Radiology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
  • Received:2010-11-02 Online:2010-12-20 Published:2010-12-20
  • Contact: JIN Zheng-yu E-mail:jin_zhengyu@163.com

Abstract: ObjectiveTo analyze the clinical value of multiple sequences derived from dual-source computed tomography (DSCT) dual-energy scan mode in detecting pancreatic adenocarcinoma. MethodsTotally 23 patients with clinically or pathologically diagnosed pancreatic cancer were enrolled in this retrospective study. DSCT (Definition Flash) was used and dual-energy scan mode was used in their pancreatic parenchyma phase scan (100kVp/230mAs and Sn140kVp/178mAs) . Mono-energetic 60kev, mono-energetic 80kev, mono-energetic 100kev, mono-energetic 120kev, linear blend image, non-linear blend image, and iodine map were acquired. pancreatic parenchyma-tumor CT value difference, ratio of tumor to pancreatic parenchyma, and pancreatic parenchyma-tumor contrast to noise ratio were calculated. One-way ANOVA was used for the comparison of diagnostic values of the above eight different dual-energy derived sequences for pancreatic cancer. ResultsThe pancreatic parenchyma-tumor CT value difference, ratio of tumor to pancreatic parenchyma, and pancreatic parenchyma-tumor contrast to noise ratio were significantly different among eight sequences (P<0.05) . Mono-energetic 60kev image showed the largest parenchyma-tumor CT value [ (77.53±23.42) HU] , and iodine map showed the lowest tumor/parenchyma enhancement ratio (0.39±0.12) and the largest contrast to noise ratio (4.08±1.46) . ConclusionsMultiple sequences can be derived from dual-energy scan mode with DSCT via multiple post-processing methods. Integration of these sequences may further improve the sensitivity of the multislice spiral CT in the diagnosis of pancreatic cancer."

Key words: X-ray computed, tomography, dual-energy, pancreatic cancer

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